Sheref Samir Mansy

BS, Ohio State University, 1997

PhD, Ohio State University, 2003

Postdoctoral Research Fellow, Harvard Medical School and Massachusetts General Hospital, 2004 –  2007

Employment

Professor of Biochemistry, 2024 - present
University of Trento

Academic Director of Research, 2023 - 2024
Professor of Chemistry, 2019 - 2024
University of Alberta

Research Leave, 2019 - 2024    
Associate Professor of Biochemistry, 2014 - 2019
Assistant Professor of Biochemistry, 2009 - 2014
University of Trento

Assistant Professor of Chemistry & Biochemistry, 2007 - 2009
University of Denver
 

Teaching

Chemical Biology II, University of Alberta, 2020-2023.
Special Topics in Chemistry/Biophysical Chemistry, University of Alberta, 2022-2024. 
University Chemistry, University of Alberta, 2019-2022.
Macromolecular Biochemistry, University of Trento, 2013-2018.
Origins of Life, University of Trento, 2018-present.
Synthetic Biology, University of Trento, 2011-2013.
Biochemistry, University of Trento, 2010-2018.
 

prebiotic chemistry, aerosols, lipid nanoparticles, synthetic biology, cell-like systems

Rossetto D, Cvjetan N, Walde P, Mansy SS (2024) Protocellular heme and iron-sulfur clusters. Acc Chem Res 57, 2293–2302. DOI: 10.1021/acs.accounts.4c00254

Sebastianelli L, Kaur H, Chen Z, Krishnamurthy R, Mansy SS (2024) A magnesium binding site and the anomeric effect regulate the abiotic redox chemistry of nicotinamide nucleotides. Chem Eur J. 30, e202400411. DOI: 10.1002/chem.202400411

Toparlaka ÖD, Sebastianelli L, Egas Ortunoc V, Karkic M, Szostak JW, Krishnamurthy R, Mansy SS (2023) Cyclophospholipids enable a protocellular life cycle. ACS Nano 17, 23772–23783. DOI: 10.1021/acsnano.3c07706

Liu Y, Liu S, Tomar A, Yen FS, Unlu G, Ropek N, Weber RA, Wang Y, Khan A, Gad M, Peng J, Terzi E, Alwaseem H, Pagano AE, Heissel S, Molina H, Allwein B, Kenny TC, Possemato RL, Zhao L, Hite RK, Vinogradova EV, Mansy SS, Birsoy K (2023) Autoregulatory control of mitochondrial glutathione homeostasis. Science 382, 820-828. DOI: 10.1126/science.adf4154
 

Nader S, Baccouche A, Connolly F, Abou-Ghanem M, Styler SA, Lewis J, Pink D, Mansy SS (2023) Model atmospheric aerosols convert to cell-sized vesicles upon entry into lipid coated aqueous solution. ACS Earth Space Chem 7, 252–259. DOI: 10.1021/acsearthspacechem.2c00328

American Chemical Society (ACS)

International Society for the Study of the Origin of Life (ISSOL)

Simons Investigator, 2013-2024
Armenise - Harvard Foundation Career Development Award, 2009-2014
TED Fellow, 2012

IUPAB2024 (International Union for Pure and Applied Biophysics), Kyoto, Japan, 26 June 2024.
Toward the understanding and engineering of complex systems: materials to life, Tokyo, Japan, 22 June
2024 Astrobiology and Origins of Life Conference, Yildiz Technical University Biotechnology and Genetics Society, Turkey, 11 Feb 2024.
Origins of Life Donostia Meeting 2023 (OLDM'23), San Sebastian, Spain, scheduled for 4 Oct 2023.
Life in the Universe Workshop, Cambridge, MA USA, 14 Sep 2023.
HFSP Symposium 2023, crossing the barrier: horizontal gene transfer between synergistic protocells, Strasbourg, France, 4 May 2023.
Centre for Molecular Simulation, University of Calgary, 24 April 2023
Penn State University, Astrobiology Hour, 19 April 2023
University of Toronto Mississauga, Department of Chemical & Physical Sciences, Toronto, Canada, 14 September 2022.
Towards Molecular Complexity: At the crossroads between astrophysics and biochemistry, Heidelberg, Germany, 3 May 2022.
Astrobiology program, University of Washington, Seattle, USA, 26 April 2022.
Keynote, University of Trento, Annual conference held by the PhD program in biomolecular sciences for the opening of the academic year, 21 February 2022.
Keynote: XIXth International Conference on the Origins of Life, 19 October 2021.
ISSET Space Exploration Symposium 2021, Edmonton, Canada, 7 October 2021.
The Molecular Origins of Life, Munich 2021 virtual conference, 27 August 2021.
Synthetic Life: ACDC Summer School, 26 August 2021.
Goldschmidt 2021, Prebiotic Chemistry and Early Earth Environments: How the Earth Gave Rise to Life, 9 July 2021.
Plenary: 2021 Summer School in Protocell Models: Coacervates and Vesicles, Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Dresden, Germany, 6 July 2021.
Juan Perez-Mercader, Harvard University, 3 June, 2021.
Armenise-Harvard Foundation, 31 March 2021
From soft matter to protocell, Tokyo, Japan, 29 October 2020.
Lorentz center, Reconstituting Biology 2020 (online), Leiden, the Netherlands, 30 June 2020.
Earth-Life Science Institute (ELSI) Extending Views of Catalysis Symposium, Tokyo, Japan, 4 Feb 2020.
Astrobiology session at Japan Geoscience Union (JpGU 2019), Makuhari Messe, Chiba, Japan, 30 May 2019.
Earth-Life Science Institute (ELSI), Tokyo Institute of Technology, Japan, 28 May 2019.
Plenary: 5th International Conference of Cell Biology, Krakow, Poland, 12 May 2019.
Delft University of Technology, Bionanoscience Department, 10 May 2019.
Max Planck Institute for Developmental Biology, Tübingen, Germany, 26 Mar 2019.
University of South Bohemia, Czech Republic, 12 Feb 2019.

Co-chair of Synthetic Biology session, 21st IUPAB (International Union of Pure and Applied Biophysics), Kyoto, Japan, 26 June 2024.
Councillor, ISSOL (International Society for the Study of the Origin of Life - The International Astrobiology Society), 2023-2026.
Organizing Committee Member, Origins of Life Donostia Meeting 2023 (OLDM'23), San Sebastian, Spain, 2-4 Oct 2023.
Editorial Advisory Board Member of ChemSystemsChem (Chemistry Europe, Wiley-VCH), 2023 - 2026.

International Advisory Editorial Board Member of Advanced Biosystems (Wiley), 2018 - present.